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U-M Scientists develop first micro-machined mechanical Cochlea - Vom 02.02.2005

The University of Michigan news service, Feb. 2, 2005

U-M scientists develop first micro-machined mechanical cochlea

ANN ARBOR, Mich.-Scientists at U-M have developed the first micro-machined, life-sized, mechanical cochlea, the tiny organ responsible for converting acoustic vibrations into electrical signals for the brain to "read" and interpret as different sounds.
Most people with hearing loss have lost the ability to translate acoustic sound waves into electrical signals for the brain, so developing a device capable of simulating this function is an important step in the effort to help at least some of the estimated 560 million people who will experience hearing loss by this year. While the U-M system is not yet ready for use as an implant, the 3-centimeter device could potentially be used as part of a cochlear implant. More immediate applications include a low-power sensor for military or commercial applications, said College of Engineering associate professor Karl Grosh.
The three advantages of the mechanical cochlea built at U-M are its life-sized dimensions, its suitability for mass production, and its use of a unique low-power mechanical method to do acoustic signal processing, Grosh said. The human cochlea is a snail-shaped organ measuring about a cubic centimeter in the inner ear. If you unwind the spiral, it would equal the length of the U-M mechanical cochlea. Researchers micro-machined the device using a technique similar to those used to make integrated circuits, which means it can be mass produced.
The mechanical cochlea works in the same way as its biological counterpart. In the biological cochlea, the basilar membrane, which winds along the cochlear spiral, is stiffer at the base and becomes softer as it approaches the center. In the engineered cochlea developed by Grosh and doctoral student Robert White, a fluid-filled duct etched onto a chip acts as the cochlear spiral. When sound waves enter the mechanical cochlea's input membrane, a wave is created, which travels down the duct, interacting with a tapered micro-machined membrane, analogous to the basilar membrane. This process allows the device to separate different frequency tones. In the biological cochlea, sensory hair cells in the spiral detect the sound waves traveling through the fluid, and translate the sound waves into electrical signals, which the auditory nerve carries to the brain. The ear hears different sounds depending on where the wave vibrates in the cochlea.
The goal is to use the mechanical cochlea as a sensitive microphone, perhaps in tandem with a cochlear implant, Grosh said, the same way an external microphone, a microprocessor and an antenna work together in present implants. Cochlear implants work by sending signals for different frequencies to electrodes implanted in the cochlear spiral. The auditory nerves then transport these signals to the brain. Researchers are adding arrays of sensors to the mechanical cochlea, which would make it possible to use the new device to drive the electrodes in a cochlear implant.
Grosh and White co-authored a paper "Microengineered Hydromechanical Cochlear Model," which appeared in the Proceedings of the National Academy of Sciences, Feb. 1, 2005.
The work is primarily funded by the National Science Foundation and the Office of Naval Research.
The University of Michigan College of Engineering is ranked among the top engineering schools in the country. Michigan Engineering boasts one of the largest research budgets of any public university, at $135 million for 2004. Michigan Engineering has 11 departments and two NSF Engineering Research Centers. Within those departments and centers, there is a special emphasis on research in three emerging industries: Nanotechnology and integrated microsystems; cellular and molecular biotechnology; and information technology. The College is seeking to raise $110 million for Capital building projects and program support in these areas to further research discovery. The CoE's goal is to advance academic scholarship and market cutting edge research to improve public heath and well-being.
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